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The pivotal ANDROMEDA-SHOCK study (2019) demonstrated a decreased mortality rate of eight percentage points among patients with septic shock whose treatment involved a resuscitation strategy targeting capillary refill time (CRT) normalization, compared with a strategy focused on blood lactate levels. Subsequently, the Surviving Sepsis Campaign added CRT monitoring as part of standard practice for treating sepsis.  


This study and the update to clinical guidance directly reinforce the value of the ProMedix FlowSense CRT detector that Matthew Hansen MD, MCR and David Sheridan MD, MCR envisioned in 2015. Drs. Hansen and Sheridan’s pursuit of an accurate, digital measure of capillary refill time, designed to assist in the diagnosis and treatment of diseases ranging from sepsis to dehydration, was developed in concert with Dr. Baker and Welch Allyn. The team filed their first patent in 2016; their first research paper was published the following year. Subsequent development enabled them to refine their discovery, leading to the FlowSense CRT detector, which currently supports multiple patient studies.  


The problem with CRT monitoring lies in the enormous variability between different provider’s measurements and even between different trials by the same clinician.  


The next evolution: ProMedix FlowSense CRT Sensor  


The FlowSense CRT sensor standardizes CRT monitoring and obtains accurate, consistent results. Building on the ANDROMEDA-SHOCK study, ProMedix has launched a prospective, observational study in the ER to determine the ability of the device to further improve early sepsis detection and increase sepsis survival rates.

Why FlowSense?

Patients and hospital systems will greatly benefit as our technology helps provide more reliable sepsis diagnoses.  


Sepsis represents a national healthcare crisis. With 30-40% of hospital mortality associated with septic shock, the World Health Assembly (WHA) and the World Health Organization (WHO) in 2017 made sepsis a global health priority and adopted a resolution that pushed for improved prevention, diagnosis, and treatment.   


In addition, sepsis is one of the most expensive diseases for a hospital system, costing $24 billion per year.    


The Andromeda Shock Study showed that treating patients based on CRT provides better outcomes than when treating based on blood lactate levels.  Our device will help healthcare workers identify sepsis in a timely and noninvasive manner. It can also aid in resuscitation by monitoring peripheral perfusion from the bedside.

Our Founders

David Sheridan MD, MCR

President

Associate Professor of Emergency Medicine, OHSU


Co-Founder IDEA-EM

Matthew Hansen MD, MCR

CMO

Associate Professor of Emergency Medicine, OHSU  


Co-Founder IDEA-EM 


Our Team

Scott Filer MPH, MBA, CTBS

CEO

Co-Founder Force Diagnostics 

 

Former Staff Scientist at Argonne National Laboratory 

Steven Baker PhD, AAMIF

CTO

Clinical Assistant Professor, OHSU  


Former Senior Principal Engineer at Welch Allyn and Hillrom

Ravi Samatham PhD

Senior Research Engineer

Image analysis & signal processing, OHSU

Jordan Gillespie

Research Assistant

Future medical student, OHSU

Dimitra Georganopoulou

Healthtech Startup Mentor

General Partner, Qral Ventures  


Chief Business Officer (CBO) in select portfolio companies  


Member of the Innovation Faculty team for MIT’s LinQ Catalyst program

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